Tyr also appears in the Dungeons and Dragons ruleset Forgotten Realms and in Bioware's popular videogame Neverwinter Nights, based off this campaign setting. Tyr is the God of Justice and Right; his city is Neverwinter, though there are temples to him in most other cities, and he is most often followed by paladins and others aligned Lawful Good. The game-Tyr has also lost his right hand, but this time by choice. He is sometimes referred to as Tyr One-Handed.

In Neverwinter Nights, your character has prolonged interaction with one of Tyr's greater paladins, Lady Aribeth de Tylmarande of Neverwinter. The Temples of Tyr in various locales provide safe haven, healing, and supplies.