"The Mutations" is a novel by Jorge Comensal, published in 2016 in Mexico as "Las Mutaciones", and published in its English translation in 2019. The novel tells the story of Ramon Martinez, a Mexican lawyer with tongue cancer, and how his cancer diagnosis and treatment affects his family. The novel would probably best be described as a black comedy.
There are several things going on in this novel. The main plot centers around Ramon and his family, but there are two parallel subplots, barely touching the main plot, where we follow the life of Ramon's therapist as she treats other patients, and of the doctor who thinks that samples of Ramon's tongue cancer will lead to a medical breakthrough. All of this is described in short vignettes that were amusing for me, and might have been even more funny in translation, and with more context. But despite these side stories, the main story is about Ramon, and how his family's maid buys him a parrot (despite it being a possible source of infection), whose foul mouth and funny habits keep him amused while he worries about his deteriorating health and financial status. The novel's plot arc is told mostly through short episodes, and while there is much talk of the psychology and spiritual aspects of mortality, I wouldn't describe the book as having any overarching statement to make about those things. Ramon is an atheist in a religious society, and his maid is a devout woman, but while this is brought up as an amusing conflict of backgrounds, it is never brought to a conclusion.
One thing that a reader from the United States (or other countries) might wonder is how much does the Mexican setting change the novel. And the answer is, only slightly. Despite most Americans thinking of Mexico in terms of its security situation, the novel only mentions it in passing. Ramon's older brother is stated to be a corrupt businessman, and several times the idea of bribing officials comes up, but in general, this is a story of someone in a relatively stable and predictable world suddenly having to face morality---the same way an American work of literary fiction might deal with the concept of mortality. Neither Mexico's religious and family oriented culture, or the lack of security or infrastructure, are important in this story, which is basically the story of a modern individual facing death.